Induction of immune responses in vivo with small numbers of veiled (dendritic) cells.
نویسندگان
چکیده
منابع مشابه
Role of CD8a1 and CD8a2 dendritic cells in the induction of primary immune responses in vivo
Data from adoptive transfer of mature dendritic cells (DC) indicate that they are responsible for the induction of primary immunity. Two subclasses of DC have been recently identified in spleen that differ in their phenotype and in certain regulatory features. In vitro, both subsets have the capacity to activate naive T cells, although CD8a1 DC have been shown to induce T cell apoptosis and to ...
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Vaccination of patients with cancer using dendritic cells (DCs) was shown to be effective for B-cell lymphoma and malignant melanoma. Here we provide evidence that patients with advanced breast and ovarian cancer can be efficiently vaccinated with autologous DCs pulsed with HER-2/neu- or MUC1-derived peptides. Ten patients were included in this pilot study. The DC vaccinations were well tolerat...
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background: dendritic cells (dcs), as the managers of the immune response, have a crucial role in forming the direction and nature of the immune response. some compounds such as 1,25-dihydroxycholecalciferol affect the function of dcs and can be used to shift the immune functions toward favorite directions. the aim of this study was to investigate the in vivo effects of 1, 25- dihydroxycholecal...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1983
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.80.19.6032